SCHEMBL1053945

SCHEMBL1053945

C=CCc1c(OC)ccc(O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
ALOX5 P09917 4/20 0.56
CYP3A4 P08684 2/20 0.56
PTGS1 P23219 2/20 0.56
AR P10275 1/20 0.56
TRPM8 Q7Z2W7 1/20 0.56
GABRA1 P14867 3/20 0.54
GABRB2 P47870 3/20 0.54
KDM4E B2RXH2 3/20 0.48
HPGD P15428 2/20 0.48
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
CNR2 P34972 1/20 0.47
CETP P11597 3/20 0.47
TNKS O95271 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
HIF1A Q16665 1/20 0.44
EPAS1 Q99814 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16863704 0.87 ALDH1A1 (0.57) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL16625547 0.86 ALDH1A1 (0.56) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL2051289 0.81 ALDH1A1 (0.48) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL3333141 0.80 ERN1 (0.50) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL13030504 0.79 ALDH1A1 (0.46) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL3958076 0.79 MAPT (0.49) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL2479613 0.79 ALDH1A1 (0.52) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL1413853 0.78 SRD5A1 (0.49) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL14615019 0.78 GABRA1 (0.43) ALDH1A1ALOX5CYP3A4PTGS1AR
SCHEMBL3956835 0.78 MEN1 (0.45) ALDH1A1ALOX5CYP3A4PTGS1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2318477-B1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MAT USA INC (US) 2019-06-05 EP disclosed
US-8252704-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2012-08-28 US disclosed
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-10-27 US disclosed
US-7985350-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-07-26 US disclosed
EP-2318477-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FujiFilm Electronic Materials USA, Inc. (US) 2011-05-11 EP disclosed
US-20110091651-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-04-21 US disclosed
US-7871536-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-01-18 US disclosed
WO-2010005937-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2010-01-14 WO disclosed
US-20090291210-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives GPX4, GPX1, NFE2L2 ALDH1A1 69/4885ALOX5 60/4885CYP3A4 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.