Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.36 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889297 | 1.00 | MAOA (0.38) | MAOAMAOBKDM1ATET3KMT2A | |
| SCHEMBL10539678 | 0.83 | GSK3B (0.32) | MAOAMAOBALDH1A1MAPK1 | |
| SCHEMBL11451364 | 0.78 | KMT2A (0.46) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL17764152 | 0.77 | CCR2 (0.44) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL9753539 | 0.75 | KMT2A (0.43) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL11311571 | 0.74 | SLC6A3 (0.39) | KMT2A | |
| SCHEMBL10543020 | 0.73 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL10545643 | 0.73 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL10543614 | 0.73 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL990390 | 0.71 | TET3 (0.48) | MAOAMAOBKDM1ATET3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855446-A | Process for the resolution of racemates using lactone esters | THE SHERWIN WILLIAMS COMPANY (US) | 1989-08-08 | — | — | US | claimed |
| EP-0060445-B1 | PROCESS FOR THE RESOLUTION OF RACEMATES AND LACTONE ESTERS USED IN SAID PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0060445-A1 | Process for the resolution of racemates and lactone esters used in said process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | claimed |
| US-4855446-A | Process for the resolution of racemates using lactone esters | THE SHERWIN WILLIAMS COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0043187-B1 | PESTICIDAL CYCLOBUTYL CARBOXYLIC ESTER COMPRISING COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1986-05-14 | — | — | EP | disclosed |
| EP-0044718-B1 | PESTICIDAL PENTAFLUOROBENZYL ESTERS OF CYCLOALKYL CARBOXYLIC ACIDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1985-11-13 | — | — | EP | disclosed |
| US-4540710-A | Insecticidal ester enantiomers | THE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1985-09-10 | — | — | US | disclosed |
| US-4501908-A | 2,3-Isopropylidene ribonic acid, 1,4-lactones | HOFFMANN-LA ROCHE INC. (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0060445-B1 | PROCESS FOR THE RESOLUTION OF RACEMATES AND LACTONE ESTERS USED IN SAID PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-08-01 | — | — | EP | disclosed |
| US-4391820-A | Insecticidal ester enantiomers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1983-07-05 | — | — | US | disclosed |
| US-4390715-A | INSECTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1983-06-28 | — | — | US | disclosed |
| EP-0060445-A1 | Process for the resolution of racemates and lactone esters used in said process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | disclosed |
| EP-0044718-A2 | Pesticidal pentafluorobenzyl esters of cycloalkyl carboxylic acids | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-01-27 | — | — | EP | disclosed |
| EP-0043187-A1 | Pesticidal cyclobutyl carboxylic ester comprising compositions | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-01-06 | — | — | EP | disclosed |