SCHEMBL1054409

SCHEMBL1054409

Fc1ccnc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 2/20 0.56
LOXL2 Q9Y4K0 1/20 0.52
HTR1A P08908 2/20 0.48
ADRA1D P25100 2/20 0.48
ADRA1A P35348 2/20 0.48
ADRA1B P35368 2/20 0.48
MAPT P10636 4/20 0.48
KDM4E B2RXH2 2/20 0.48
FERMT2 Q96AC1 1/20 0.47
TGFBR1 P36897 2/20 0.44
GRM4 Q14833 1/20 0.44
CYP3A4 P08684 1/20 0.43
CYP1A2 P05177 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
PTK2B Q14289 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30948576 1.00 NCF1 (0.56) NCF1LOXL2HTR1AADRA1DADRA1A
Acetic Acid SCHEMBL27876855 0.87 SLC22A12 (0.46) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL2265617 0.84 KDM4E (0.58) NCF1LOXL2MAPTKDM4ECYP3A4
SCHEMBL30129911 0.84 KDM4E (0.58) NCF1LOXL2MAPTKDM4ECYP3A4
SCHEMBL27288809 0.77 TGFBR1 (0.58) NCF1LOXL2MAPTKDM4ETGFBR1
SCHEMBL31301051 0.76 LMNA (0.56) NCF1MAPTKDM4ECYP3A4MEN1
SCHEMBL29699887 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL27917128 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL1227713 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL134737 0.73 NCF1 (0.58) NCF1LOXL2HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677762-B Benzenesulfonyl amino phosphonate derivative and preparation method and application thereof 遵义医科大学 2024-06-25 CN claimed
CN-117986186-A Quinoline chemical tracer for multistage fracturing, tracing method, fracturing fluid and application 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-112939857-A Synthetic method of alkylated quinoline compound 中国科学院大连化学物理研究所 2021-06-11 CN claimed
CN-108107142-B Analysis method of surfactant in wax removal water 上海微谱化工技术服务有限公司 2020-05-22 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-12522595-B2 Bicyclic ether O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2026-01-13 US disclosed
EP-3838900-B1 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF ZHANGZHOU PIEN TZE HUANG PHARM (CN) 2025-02-12 EP disclosed
US-11981671-B2 Bicyclic pyrazolyl amines as CDK2 inhibitors INCYTE CORPORATION (US) 2024-05-14 US disclosed
CN-117986186-A Quinoline chemical tracer for multistage fracturing, tracing method, fracturing fluid and application 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-117861697-A Preparation method of 3D tungsten carbide cocatalyst and application of cocatalyst in catalyzing Fenton reaction 华南理工大学 2024-04-12 CN disclosed
CN-117680086-A Preparation method and application of magnetic porous silicon composite material 重庆科技大学 2024-03-12 CN disclosed
CN-112654616-B 3-aryloxy-3-aryl-propylamines and application thereof 漳州片仔癀药业股份有限公司 2024-03-12 CN disclosed
US-5204348-A Quinoline derivatives MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-20 US disclosed
US-5112817-A Anticancer Drug Potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-12 US disclosed
EP-0363212-A2 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-04-11 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981671-B2 Bicyclic pyrazolyl amines as CDK2 inhibitors CDK2, CCNI, CDK1 NCF1 1541/4885LOXL2 3052/4885HTR1A 4013/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR NCF1 937/4885LOXL2 2968/4885HTR1A 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.