Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26207348 | 0.67 | MAOA (0.37) | ALDH1A1GRM2MAOAMAOBHTR2A | |
| SCHEMBL1012684 | 0.66 | HSD17B10 (0.31) | MAOAMAOBKDM1A | |
| SCHEMBL11403757 | 0.66 | ALDH1A1 (0.59) | ALDH1A1CYP1A1CYP1B1CYP3A4CA2 | |
| SCHEMBL11526269 | 0.65 | CHRNB2 (0.41) | CYP1A1CYP1B1CYP3A4CA2HTR2A | |
| SCHEMBL4402559 | 0.65 | MTNR1A (0.43) | HTR2AHTR2C | |
| SCHEMBL25429872 | 0.64 | MEN1 (0.41) | MAOAMAOBHTR2AHTR2C | |
| SCHEMBL30550467 | 0.64 | MAOA (0.40) | MAOAMAOBCA2 | |
| SCHEMBL1119927 | 0.64 | CA2 (0.56) | ALDH1A1CYP1A1CYP1B1CYP3A4CA2 | |
| SCHEMBL4297601 | 0.64 | ALDH1A1 (0.56) | ALDH1A1CYP1A1CYP1B1CYP3A4CA2 | |
| SCHEMBL31562352 | 0.63 | CYP3A4 (0.41) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822804-A | 5,6,7,-trinor-4,8-inter-m-phenylene 2-nor PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4564620-A | 5,6,7,-Trinor-4,8-inter-m-phenylene PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1986-01-14 | — | — | US | disclosed |