⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565134 | 0.81 | GAA (0.40) | — | |
| SCHEMBL10566312 | 0.79 | PDXK (0.31) | — | |
| SCHEMBL10563076 | 0.77 | LMNA (0.30) | — | |
| SCHEMBL7422510 | 0.62 | ADORA3 (0.48) | — | |
| SCHEMBL10564142 | 0.60 | KMT2A (0.43) | — | |
| SCHEMBL31586653 | 0.55 | PIK3CD (0.31) | — | |
| SCHEMBL203826 | 0.54 | TGFBR1 (0.40) | — | |
| SCHEMBL16102904 | 0.54 | HTT (0.51) | — | |
| SCHEMBL15650618 | 0.54 | — | — | |
| SCHEMBL17076748 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837238-A | Pharmacologically useful pyrazolopyridines | BEECHAM GROUP P.L.C. (GB) | 1989-06-06 | — | — | US | disclosed |
| EP-0193329-A2 | Pyrazolopyridines, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-09-03 | — | — | EP | disclosed |