Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558483 | 0.89 | GLA (0.41) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10564289 | 0.86 | MAPT (0.39) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9602523 | 0.81 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9866556 | 0.80 | PRKCZ (0.38) | PRKCZLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10561129 | 0.80 | CES2 (0.40) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7287572 | 0.78 | LMNA (0.40) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10560169 | 0.78 | KDM4E (0.37) | PRKCZSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL10562574 | 0.77 | CES2 (0.39) | LMNASMN1; SMN2MAPTGAAHTT | |
| SCHEMBL9864982 | 0.77 | KDM4E (0.40) | PRKCZLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10561234 | 0.75 | MAPT (0.36) | SMN1; SMN2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |