Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568361 | 0.90 | PTGDR2 (0.42) | RAB9AMAPTMEN1KMT2APDE5A | |
| SCHEMBL10568339 | 0.90 | PTGDR2 (0.42) | RAB9AMAPTMEN1KMT2APDE5A | |
| SCHEMBL10565925 | 0.84 | DRD2 (0.49) | RAB9AMAPTMEN1KMT2AGAA | |
| Oxalic Acid SCHEMBL10567218 | 0.82 | ALDH1A1 (0.48) | MAPTMEN1KMT2AGAAHTT | |
| Oxalic Acid SCHEMBL10567216 | 0.82 | ALDH1A1 (0.48) | MAPTMEN1KMT2AGAAHTT | |
| SCHEMBL10566353 | 0.82 | ALDH1A1 (0.44) | RAB9AMAPTMEN1KMT2AGAA | |
| SCHEMBL10566298 | 0.79 | ADRB2 (0.43) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10566300 | 0.79 | ADRB2 (0.43) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10567624 | 0.79 | ADRB2 (0.43) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| Oxalic Acid SCHEMBL10564624 | 0.78 | ATM (0.45) | MEN1KMT2AHTTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843085-A | LOCAL ANESTHETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0297613-A2 | Pyridine derivatives, process for production thereof and pharmaceutical composition containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |