Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568339 | 1.00 | PTGDR2 (0.42) | PTGDR2PDE5ARAB9AS1PR4GRK6 | |
| SCHEMBL10566344 | 0.90 | RAB9A (0.41) | PTGDR2PDE5ARAB9AS1PR4GRK6 | |
| SCHEMBL10566765 | 0.83 | DRD2 (0.51) | PTGDR2RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10566772 | 0.83 | DRD2 (0.51) | PTGDR2RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10727028 | 0.82 | GRK6 (0.52) | GRK6TTRKMT2AMEN1ALDH1A1 | |
| SCHEMBL10577903 | 0.81 | ALDH1A1 (0.43) | PTGDR2RAB9AEIF4A1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL10566726 | 0.81 | DRD2 (0.49) | PTGDR2RAB9AKMT2AMEN1ALDH1A1 | |
| Oxalic Acid SCHEMBL10566732 | 0.81 | DRD2 (0.49) | PTGDR2RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10568350 | 0.81 | XDH (0.48) | RAB9AKMT2AMEN1ALDH1A1NPC1 | |
| Oxalic Acid SCHEMBL10577726 | 0.80 | ALDH1A1 (0.46) | PTGDR2RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843085-A | LOCAL ANESTHETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0297613-A2 | Pyridine derivatives, process for production thereof and pharmaceutical composition containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |