Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183703 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| SCHEMBL27767390 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| SCHEMBL368887 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| SCHEMBL8757855 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| SCHEMBL30618844 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| SCHEMBL714226 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| Biphenyl SCHEMBL239496 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| Biphenyl SCHEMBL29265378 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| Biphenyl SCHEMBL27348783 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TSHRPTGS2TP53HDAC2 | |
| Biphenyl SCHEMBL28098304 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TSHRPTGS2TP53HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954988-A | Functionalized elastomer and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119954989-A | Functionalized polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| EP-3822308-B1 | RECYCLED RUBBER | IND TECH RES INST (TW) | 2025-03-05 | — | — | EP | claimed |
| US-12195561-B2 | Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers | SYNTHOS S.A. (PL) | 2025-01-14 | — | — | US | claimed |
| US-11993620-B2 | Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers | SYNTHOS S.A. (PL) | 2024-05-28 | — | — | US | claimed |
| EP-3915808-B1 | FUNCTIONALIZED INITIATOR, METHOD OF MAKING AN INITIATOR AND FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER (US) | 2024-01-31 | — | — | EP | claimed |
| CN-113329890-B | Bis-silylamino functionalized conjugated dienes, preparation thereof and use thereof in rubber production | 西索斯公司 | 2023-10-20 | — | — | CN | claimed |
| CN-112812358-B | Reclaimed rubber | 财团法人工业技术研究院 | 2023-05-09 | — | — | CN | claimed |
| EP-3911525-B1 | BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS | Synthos Sa (PL) | 2023-03-08 | — | — | EP | claimed |
| CN-112955332-B | Amino silyl functionalized conjugated dienes, their preparation and use in the manufacture of rubber | 西索斯公司 | 2023-02-21 | — | — | CN | claimed |
| US-20180072101-A1 | ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS | SYNTHOS S.A. (PL) | 2018-03-15 | — | — | US | claimed |
| EP-3280766-A1 | ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS | Synthos S.A. (PL) | 2018-02-14 | — | — | EP | claimed |
| US-9574042-B2 | Functionalized polymer, rubber composition and pneumatic tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2017-02-21 | — | — | US | claimed |
| US-20160376394-A1 | FUNCTIONALIZED POLYMER, RUBBER COMPOSITION AND PNEUMATIC TIRE | GOODYEAR TIRE & RUBBER (US) | 2016-12-29 | — | — | US | claimed |
| WO-2016162528-A1 | ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS | SYNTHOS S.A. (PL) | 2016-10-13 | — | — | WO | claimed |
| US-9428628-B2 | Functionalized polymer, rubber composition and pneumatic tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2016-08-30 | — | — | US | claimed |
| US-20160053077-A1 | FUNCTIONALIZED POLYMER, RUBBER COMPOSITION AND PNEUMATIC TIRE | GOODYEAR TIRE & RUBBER COMPANY, THE | 2016-02-25 | — | — | US | claimed |
| EP-2987812-A1 | FUNCTIONALIZED POLYMER, RUBBER COMPOSITION AND PNEUMATIC TIRE | The Goodyear Tire & Rubber Company (US) | 2016-02-24 | — | — | EP | claimed |
| US-7485684-B2 | Functionalization of living rubbery polymers with nitrones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2009-02-03 | — | — | US | claimed |
| US-20070004869-A1 | Functionalization of living rubbery polymers with nitrones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072101-A1 | ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS | VCL, TIPRL, TTL | ALDH1A1 4052/4885TSHR 3890/4885PTGS2 2895/4885 |
| US-12195561-B2 | Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers | CARM1, ILK, RIF1 | ALDH1A1 473/4885TSHR 3100/4885PTGS2 1449/4885 |
| US-11993620-B2 | Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers | LTA, RALA, BOLA2; BOLA2B | ALDH1A1 681/4885TSHR 3044/4885PTGS2 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.