Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572988 | 0.84 | NPBWR1 (0.34) | NPBWR1TRPV1METAP2SCDMAPT | |
| SCHEMBL10576345 | 0.80 | SCN10A (0.38) | SCN10AKCNH2NPBWR1TRPV1METAP2 | |
| SCHEMBL10574081 | 0.76 | AMY1A (0.56) | NPBWR1AMY1A | |
| SCHEMBL10573910 | 0.76 | SLC2A1 (0.62) | NPBWR1TRPV1ALDH1A1KDM4ENPC1 | |
| SCHEMBL10580044 | 0.74 | AMY1A (0.41) | NPBWR1TRPV1NPC1RAB9AAMY1A | |
| SCHEMBL10693991 | 0.74 | AMY1A (0.45) | NPBWR1TRPV1AMY1A | |
| SCHEMBL10577412 | 0.74 | F2 (0.41) | SCN10AKCNH2NPBWR1METAP2SCD | |
| SCHEMBL10579204 | 0.74 | ALOX5 (0.62) | NPBWR1TRPV1ALDH1A1KDM4EAMY1A | |
| SCHEMBL10577479 | 0.74 | NPBWR1 (0.67) | KCNH2NPBWR1TRPV1SCDALDH1A1 | |
| SCHEMBL10573938 | 0.73 | MAPT (0.59) | SCN10AKCNH2NPBWR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |