Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576208 | 0.84 | AMY1A (0.34) | AMY1A | |
| SCHEMBL10580031 | 0.84 | AMY1A (0.46) | AMY1AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL10577465 | 0.75 | NPBWR1 (0.53) | KDM4EALDH1A1MAPTNPBWR1NPC1 | |
| SCHEMBL10574074 | 0.74 | AMY1A (0.47) | AMY1ASLC2A1NR1I2 | |
| SCHEMBL10415589 | 0.74 | PDE5A (0.43) | AMY1AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL10573902 | 0.74 | NPC1 (0.54) | KDM4EALDH1A1GAAMAPTNPBWR1 | |
| SCHEMBL10575959 | 0.73 | AMY1A (0.38) | AMY1ASLC2A1NPC1RAB9ANR1I2 | |
| SCHEMBL10576332 | 0.73 | AMY1A (0.38) | AMY1ASLC2A1NPC1RAB9A | |
| SCHEMBL10579198 | 0.73 | ALOX5 (0.53) | AMY1AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL10577409 | 0.73 | AMY1A (0.36) | AMY1AKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |