Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | PLG | P00747 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | PLAT | P00750 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577412 | 0.91 | F2 (0.41) | AMY1AF2F10PLGPLAU | |
| SCHEMBL10578002 | 0.83 | AMY1A (0.32) | AMY1ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL10579325 | 0.78 | DGAT1 (0.51) | SMN1; SMN2HPGDALDH1A1GAAHDAC6 | |
| SCHEMBL10577465 | 0.77 | NPBWR1 (0.53) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL10580031 | 0.76 | AMY1A (0.46) | AMY1ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL10573929 | 0.76 | MAPT (0.44) | SMN1; SMN2HPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL10576078 | 0.75 | HDAC6 (0.52) | PLAUPRSS1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL10576332 | 0.75 | AMY1A (0.38) | AMY1ANPC1RAB9A | |
| SCHEMBL10575682 | 0.74 | HDAC6 (0.40) | SMN1; SMN2HPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL10573939 | 0.74 | KDM4E (0.49) | SMN1; SMN2HPGDNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |