Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | PLG | P00747 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PLAT | P00750 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577409 | 0.91 | AMY1A (0.36) | F2F10PLGPLAUPRSS1 | |
| SCHEMBL10578009 | 0.83 | THRB (0.36) | F2F10PLGPLAUPRSS1 | |
| SCHEMBL10579334 | 0.78 | DGAT1 (0.64) | ALDH1A1SMN1; SMN2NPBWR1KCNH2DGAT1 | |
| SCHEMBL10577479 | 0.77 | NPBWR1 (0.67) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10573938 | 0.76 | MAPT (0.59) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL10576089 | 0.75 | NPBWR1 (0.64) | PLAUPRSS1KDM4EALDH1A1GAA | |
| SCHEMBL10580044 | 0.75 | AMY1A (0.41) | F2F10PLGPLAUPRSS1 | |
| SCHEMBL10575692 | 0.74 | NPBWR1 (0.49) | KDM4EALDH1A1NPC1NPBWR1KCNH2 | |
| SCHEMBL10573947 | 0.74 | NPC1 (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL10575984 | 0.74 | SCN10A (0.38) | KDM4EALDH1A1GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |