Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 6/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578004 | 0.91 | NPBWR1 (0.58) | NPBWR1DGAT1KCNH2SOAT1TRPV1 | |
| SCHEMBL10580688 | 0.91 | HDAC6 (0.52) | NPBWR1DGAT1KCNH2SOAT1TRPV1 | |
| SCHEMBL10574665 | 0.90 | NPBWR1 (0.47) | NPBWR1TRPV1HDAC6RAB9ACHEK2 | |
| SCHEMBL10574691 | 0.90 | KDM4E (0.43) | KITHDAC6RAB9A | |
| SCHEMBL10577324 | 0.89 | DGAT1 (0.46) | NPBWR1DGAT1KCNH2TRPV1HDAC6 | |
| SCHEMBL10578691 | 0.89 | GUSB (0.43) | NPBWR1HDAC6TNKSTNKS2RAB9A | |
| SCHEMBL10578441 | 0.89 | HDAC6 (0.46) | NPBWR1DGAT1KCNH2HDAC6TNKS | |
| SCHEMBL10573285 | 0.87 | TCF4 (0.45) | NPBWR1TRPV1HDAC6RAB9A | |
| SCHEMBL10574269 | 0.87 | NPC1 (0.48) | NPBWR1TRPV1HDAC6TNKSTNKS2 | |
| SCHEMBL10571887 | 0.84 | KIT (0.39) | NPBWR1DGAT1KCNH2TRPV1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |