SCHEMBL1058413

SCHEMBL1058413

COC1(OC)CCCCC1Cl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1060737 0.92
SCHEMBL7330065 0.79 MAPT (0.32)
SCHEMBL11303875 0.76
SCHEMBL9189204 0.75 MAPT (0.36) SLC6A2SLC6A4OPRM1
SCHEMBL10680456 0.73 SLC6A2 (0.33) SLC6A2SLC6A4OPRM1
SCHEMBL3246813 0.73 SLC6A4 (0.33) SLC6A2SLC6A4OPRM1
SCHEMBL940127 0.73 SLC6A4 (0.35) SLC6A2SLC6A4OPRM1
SCHEMBL1081300 0.71 MAPT (0.33)
SCHEMBL1076375 0.71
SCHEMBL16933846 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546587-B2 Method for producing acrylate derivative, acrylate derivative, and intermediate thereof KURARAY CO., LTD. (JP) 2013-10-01 US disclosed
US-8431722-B2 Acrylate ester derivatives and polymer compounds KURARAY CO., LTD. (JP) 2013-04-30 US disclosed
US-8362169-B2 Acrylate ester derivatives and polymer compounds KURARAY CO., LTD. (JP) 2013-01-29 US disclosed
US-20130005990-A1 METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF KURARAY CO., LTD. (JP) 2013-01-03 US disclosed
US-20120316349-A1 ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS KURARAY CO., LTD. (JP) 2012-12-13 US disclosed
US-8314258-B2 Method for producing acrylate derivative, acrylate derivative, and intermediate thereof KURARAY CO., LTD. (JP) 2012-11-20 US disclosed
US-20110060112-A1 ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS KURARAY CO., LTD. (JP) 2011-03-10 US disclosed
US-20110009643-A1 METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF KURARAY CO., LTD. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130005990-A1 METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF ACR, ADH1A, ALAD SLC6A2 3770/4885SLC6A4 2101/4885OPRM1 3828/4885
US-20120316349-A1 ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS ADH1A, ADH1C, ADH5 SLC6A2 4320/4885SLC6A4 3974/4885OPRM1 201/4885
US-20110060112-A1 ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS RAD51, LBR, RPLP0 SLC6A2 4670/4885SLC6A4 3383/4885OPRM1 1535/4885
US-20110009643-A1 METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF ACR, ADH1A, ALAD SLC6A2 3770/4885SLC6A4 2101/4885OPRM1 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.