Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300227 | 0.93 | — | — | |
| SCHEMBL12557618 | 0.82 | — | — | |
| SCHEMBL9152767 | 0.76 | SLC6A3 (0.38) | SLC6A4SLC6A3MAPT | |
| SCHEMBL24129062 | 0.74 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL25973802 | 0.74 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL24483580 | 0.74 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL9189204 | 0.73 | MAPT (0.36) | SLC6A4SLC6A2OPRM1MAPT | |
| SCHEMBL1058413 | 0.73 | SLC6A2 (0.31) | SLC6A4SLC6A2OPRM1 | |
| SCHEMBL10680456 | 0.71 | SLC6A2 (0.33) | SLC6A4SLC6A2OPRM1 | |
| SCHEMBL3246813 | 0.71 | SLC6A4 (0.33) | SLC6A4SLC6A3SLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226920-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO.,LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| US-7868041-B2 | Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof | XENOPORT, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090270493-A1 | CYCLIC 1-(ACYLOXY)-ALKYL PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-7569576-B2 | Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof | XENOPORT, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-7307183-B2 | Process for producing tetrabromobenzoate esters | GREAT LAKES CHEMICAL CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-20060122125-A1 | Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof | XENOPORT, INC. | 2006-06-08 | — | — | US | disclosed |
| EP-1658261-A1 | PROCESS FOR PRODUCING TETRABROMOBENZOATE ESTERS | GREAT LAKES CHEMICAL CORPORATION (US) | 2006-05-24 | — | — | EP | disclosed |
| US-7026351-B2 | Gamma-aminobutyric acid (GABA); prodrugs of gabapentin and/or pregabalin; for sustained release; for treatment of pain and epilepsy | XENOPORT, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| WO-2005016863-A1 | PROCESS FOR PRODUCING TETRABROMOBENZOATE ESTERS | GREAT LAKES CHEMICAL CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050027139-A1 | Process for producing tetrabromobenzoate esters | GLCC LAUREL, LLC | 2005-02-03 | — | — | US | disclosed |
| US-6063256-A | REDUCTION OF PHTHALIDES AND CONDENSATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-16 | — | — | US | disclosed |
| EP-0983987-A1 | Process for the preparation of alpha-diketones from ketols or from ketals of ketols | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-08 | — | — | EP | disclosed |
| EP-0832153-A4 | BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS | GREAT LAKES CHEMICAL CORP (US) | 1998-08-26 | — | — | EP | disclosed |
| EP-0825974-A4 | ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS | GREAT LAKES CHEMICAL CORP (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0832153-A1 | BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5728760-A | FLAME RETARDANTS FOR POLYURETHANES; PLASTICIZERS FOR POLYVINYL CHLORIDE, RUBBERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0825974-A1 | ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS | GREAT LAKES CHEMICAL CORPORATION (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5637757-A | REACTING TETRABROMOPHTHALIC ANHYDRIDE WITH AN ALCOHOL IN PRESENCE OF A DECARBOXYLATION CATALYST | GREAT LAKES CHEMICAL CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996032368-A1 | ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS | GREAT LAKES CHEMICAL CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996032438-A1 | BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270493-A1 | CYCLIC 1-(ACYLOXY)-ALKYL PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | GABRB1, GABRB3, GABRB2 | SLC6A4 589/4885SLC6A3 417/4885SLC6A2 715/4885 |
| US-20060122125-A1 | Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof | GABRB1, GABRB3, GABRB2 | SLC6A4 589/4885SLC6A3 417/4885SLC6A2 715/4885 |
| US-20050027139-A1 | Process for producing tetrabromobenzoate esters | TECR, ADH1C, ADH1A | SLC6A4 4270/4885SLC6A3 4665/4885SLC6A2 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.