Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 5/20 | 0.32 |
| ▸ | ALPI | P09923 | 5/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782323 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM5BCA2CHKAAR | |
| SCHEMBL11783513 | 0.72 | PTGS2 (0.40) | ALDH1A1KDM5BCA2CHKAAR | |
| SCHEMBL10589128 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM5BCA2CHKAAR | |
| SCHEMBL11783258 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM5BCHKAPOLBGAA | |
| SCHEMBL8018827 | 0.69 | MEN1 (0.45) | ALDH1A1KDM5BALPLALPIKCNQ3 | |
| SCHEMBL11784400 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KDM5BALPLALPIPKM | |
| SCHEMBL9723042 | 0.69 | KDM5B (0.39) | ALDH1A1KDM5BKCNQ3KCNQ2PKM | |
| SCHEMBL11780619 | 0.68 | LMNA (0.39) | ALDH1A1KDM5BALPLALPIGAA | |
| SCHEMBL11779175 | 0.68 | PTGS2 (0.38) | ALDH1A1KDM5BARALPLALPI | |
| SCHEMBL2608960 | 0.68 | POLB (0.41) | ALDH1A1KDM5BPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338686-A2 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1989-10-25 | — | — | EP | disclosed |