Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.33 |
| ▸ | ALPI | P09923 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782323 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM5BALPLALPICA2 | |
| SCHEMBL10589824 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM5BALPLALPICA2 | |
| SCHEMBL9730727 | 0.69 | KDM5B (0.35) | ALDH1A1KDM5BALPLALPI | |
| SCHEMBL25153650 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM5BALPLALPIAR | |
| SCHEMBL24637828 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM5BALPLALPICA2 | |
| SCHEMBL27372069 | 0.68 | ADORA2B (0.39) | ALDH1A1KDM5BCA2CHKA | |
| SCHEMBL11783513 | 0.68 | PTGS2 (0.40) | ALDH1A1KDM5BALPLALPICA2 | |
| SCHEMBL7085889 | 0.67 | TRPV4 (0.37) | ALDH1A1KDM5BALPLALPI | |
| SCHEMBL11783258 | 0.67 | ALDH1A1 (0.38) | ALDH1A1KDM5BCHKA | |
| SCHEMBL9581996 | 0.67 | HCAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338686-A2 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1989-10-25 | — | — | EP | disclosed |