Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19012588 | 0.96 | THRB (0.42) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL19012575 | 0.91 | TSHR (0.43) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL19000950 | 0.89 | TSHR (0.39) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL28388697 | 0.81 | ADRB2 (0.41) | ALDH1A1MMP8RECQLCYP3A4CYP2C9 | |
| SCHEMBL42893 | 0.80 | HCAR2 (0.51) | THRBTDP1POLBAPEX1HTT | |
| Methane SCHEMBL4468486 | 0.79 | HCAR2 (0.50) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL115658 | 0.78 | KIF11 (0.46) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL148938 | 0.77 | LMNA (0.60) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL27973892 | 0.77 | HCAR2 (0.49) | THRBTDP1POLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL8131805 | 0.77 | HCAR2 (0.49) | THRBTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298030-A2 | Process for forming images | CIBA-GEIGY AG (CH) | 1989-01-04 | — | — | EP | disclosed |