SCHEMBL1060099

SCHEMBL1060099

CC#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2OC)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK2 O00142 8/20 0.49
PYGM P11217 3/20 0.49
TYMP P19971 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1060097 1.00 TK2 (0.49) TK2PYGMTYMP
SCHEMBL27179233 1.00 TK2 (0.49) TK2PYGMTYMP
SCHEMBL1055729 0.90 TK2 (0.47) TK2PYGM
SCHEMBL1055725 0.90 TK2 (0.47) TK2PYGM
SCHEMBL6685514 0.89 TK2 (0.47) TK2PYGM
SCHEMBL6685510 0.89 TK2 (0.47) TK2PYGM
SCHEMBL10591532 0.89 TK2 (0.54) TK2PYGM
SCHEMBL9132874 0.88 TK2 (0.50) TK2PYGMTYMP
SCHEMBL9132872 0.88 TK2 (0.50) TK2PYGMTYMP
SCHEMBL1417682 0.88 TK2 (0.50) TK2PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-4727955-A1 CYSTEINE-SUBSTITUTED RSV-F PROTEINS GlaxoSmithKline Biologicals S.A. (BE) 2026-04-22 EP disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP disclosed
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-09 US disclosed
US-20260091104-A1 NUCLEIC ACID VACCINES MODERNATX, INC. (US) 2026-04-02 US disclosed
US-12582609-B2 Cancer vaccines MODERNATX, INC. (US) 2026-03-24 US disclosed
EP-4709417-A2 POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-03-18 EP disclosed
US-20050069905-A1 Detection of molecular binding events AGILENT TECHNOLOGIES, INC. 2005-03-31 US disclosed
US-20040248104-A1 Methods and reagents for profiling quantities of nucleic acids AGILENT TECHNOLOGIES, INC. 2004-12-09 US disclosed
US-20040143114-A1 Novel bicyclonucleoside analogues SANKYO COMPANY, LIMITED (JP) 2004-07-22 US disclosed
US-20030207841-A1 Novel nucleoside and oligonucleotide analogues SANKYO COMPANY LIMITED (JP) 2003-11-06 US disclosed
US-20030022150-A1 Detecting preferential bioplymers in sample; obtain nutrient broths inoculate with cells, immerse electrodes, code cells, incubate cells with substrate, monitor response, evaluate response AGILENT TECHNOLOGIES, INC. 2003-01-30 US disclosed
US-20020147332-A1 Novel nucleoside and oligonucleotide analogues SANKYO COMPANY, LIMITED (JP) 2002-10-10 US disclosed
US-6218118-B1 MIXTURE OF NATURAL AND MASS-MODIFIED GENERIC OLIGONUCLEOTIDE PRECURSORS; USING MIXTURE AND ENZYMATIC PROCESSES TO ALTER THE LENGTH, AND THUS THE MASS, OF PRECURSORS THAT ARE COMPLEMENTARY TO TARGET NUCLEIC ACID AGILENT TECHNOLOGIES, INC. 2001-04-17 US disclosed
EP-1015643-A2 METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS Hewlett-Packard Company (US) 2000-07-05 EP disclosed
WO-2000003038-A2 METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS HEWLETT-PACKARD COMPANY (US) 2000-01-20 WO disclosed
US-5459243-A Apparatus and processes for the large scale generation and transfer of diazomethane ISIS PHARMACEUTICALS, INC. (US) 1995-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES RNMT, RNGTT, METTL16 TK2 3633/4885PYGM 2866/4885TYMP 873/4885
US-12582609-B2 Cancer vaccines RNMT, MICA, NSUN2 TK2 2216/4885PYGM 4875/4885TYMP 2726/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 TK2 3425/4885PYGM 3025/4885TYMP 629/4885
US-20020147332-A1 Novel nucleoside and oligonucleotide analogues RNGTT, NSUN2, MTAP TK2 447/4885PYGM 2644/4885TYMP 37/4885
US-20260091104-A1 NUCLEIC ACID VACCINES RNMT, NSUN2, AMPD1 TK2 1560/4885PYGM 4334/4885TYMP 531/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 TK2 4100/4885PYGM 3499/4885TYMP 2162/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT TK2 1499/4885PYGM 3599/4885TYMP 450/4885
US-20030207841-A1 Novel nucleoside and oligonucleotide analogues RNGTT, NSUN2, MTAP TK2 447/4885PYGM 2644/4885TYMP 37/4885
US-20040143114-A1 Novel bicyclonucleoside analogues PURB, DUT, NSUN2 TK2 205/4885PYGM 3895/4885TYMP 29/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 TK2 2857/4885PYGM 3513/4885TYMP 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.