SCHEMBL1060246

SCHEMBL1060246

O=C(O)CCCCCBr.O=C1CCC(=O)N1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
LMNA P02545 2/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
PTGS1 P23219 4/20 0.40
PTGS2 P35354 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
HDAC11 Q96DB2 4/20 0.38
F13A1 P00488 3/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576050 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL6738514 0.94 LMNA (0.39) TSHRLMNANFKB1PMP22PTGS1
Sebacic Acid SCHEMBL28228671 0.91 TSHR (0.52) TSHRLMNANFKB1PMP22PTGS1
Octanedioate SCHEMBL6037661 0.91 TSHR (0.52) TSHRLMNANFKB1PMP22PTGS1
Octanedioate SCHEMBL1394807 0.91 TSHR (0.52) TSHRLMNANFKB1PMP22PTGS1
Azelaic Acid SCHEMBL28918234 0.91 TSHR (0.52) TSHRLMNANFKB1PMP22PTGS1
Adipic Acid SCHEMBL29427201 0.89 LMNA (0.50) TSHRLMNANFKB1PMP22PTGS1
Adipic Acid SCHEMBL906129 0.89 LMNA (0.50) TSHRLMNANFKB1PMP22PTGS1
Sebacic Acid SCHEMBL29286911 0.85 GPR84 (0.50) TSHRLMNANFKB1PMP22PTGS1
Glutarate SCHEMBL28487046 0.85 SLC22A6 (0.50) TSHRLMNANFKB1PMP22PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3141615-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2019-10-23 EP disclosed
US-20190048401-A1 OPTIMIZED REAL-TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2019-02-14 US disclosed
EP-1348713-B1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES INC (US) 2019-01-23 EP disclosed
US-10144957-B2 Optimized real time nucleic acid detection processes ENZO LIFE SCIENCES, INC. (US) 2018-12-04 US disclosed
US-10144956-B2 Processes for quantitative or qualitative detection of single-stranded or double-stranded nucleic acids ENZO BIOCHEM, INC. (US) 2018-12-04 US disclosed
EP-2366798-B1 Nucleic acid detection process involving energy transfer labels on nucleotide ENZO LIFE SCIENCES INC (US) 2017-06-28 EP disclosed
EP-1344835-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2017-06-14 EP disclosed
EP-3141615-A1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS Enzo Life Sciences, Inc. (US) 2017-03-15 EP disclosed
US-20160281146-A1 OPTIMIZED REAL TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2016-09-29 US disclosed
US-20160273028-A1 PROCESSES FOR QUANTITATIVE OR QUALITATIVE DETECTION OF SINGLE-STRANDED OR DOUBLE-STRANDED NUCLEIC ACIDS ENZO LIFE SCIENCES, INC. (US) 2016-09-22 US disclosed
US-20050004350-A1 Novel chemiluminescent reagents ENZO LIFE SCIENCES, INC. (US) 2005-01-06 US disclosed
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes ENZO LIFE SCIENCES, INC. 2004-12-16 US disclosed
US-20040229248-A1 Novel dye labeling composition ENZO LIFE SCIENCES, INC. 2004-11-18 US disclosed
US-20040230036-A1 Heterodimeric dye composition ENZO LIFE SCIENCES, INC. (US) 2004-11-18 US disclosed
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents ENZO LIFE SCIENCES, INC. 2004-10-14 US disclosed
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics ENZO LIFE SCIENCES, INC. (US) 2004-09-30 US disclosed
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample ENZO LIFE SCIENCES, INC. (US) 2004-09-09 US disclosed
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES, INC. 2003-12-04 US disclosed
EP-1348713-A2 Labeling reagents and labeled tabeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses Enzo Life Sciences, Inc. (US) 2003-10-01 EP disclosed
EP-1344835-A2 Real-time nucleic acid detection processes and compositions Enzo Life Sciences, Inc. (US) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229248-A1 Novel dye labeling composition IK, PHAX, CHLSN TSHR 4649/4885LMNA 103/4885NFKB1 3231/4885
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents PHAX, IK, CHLSN TSHR 4412/4885LMNA 72/4885NFKB1 3037/4885
US-20050004350-A1 Novel chemiluminescent reagents CHLSN, CYBA, HLCS TSHR 3308/4885LMNA 48/4885NFKB1 3015/4885
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample RNGTT, POLRMT, CHLSN TSHR 4294/4885LMNA 165/4885NFKB1 2681/4885
US-20040230036-A1 Heterodimeric dye composition IK, CHLSN, CRY2 TSHR 4498/4885LMNA 230/4885NFKB1 2878/4885
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses POLRMT, CHLSN, PHAX TSHR 3683/4885LMNA 82/4885NFKB1 3621/4885
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes IK, RBM25, CHLSN TSHR 3063/4885LMNA 238/4885NFKB1 4171/4885
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics CHLSN, DDB1, PROC TSHR 4662/4885LMNA 365/4885NFKB1 3199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.