Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490230 | 0.84 | HDAC4 (0.42) | HDAC4HSD11B1CCR2 | |
| SCHEMBL10608672 | 0.84 | LMNA (0.38) | ALDH1A1HDAC4TSHROPRM1 | |
| SCHEMBL6036780 | 0.81 | HDAC4 (0.47) | ALDH1A1HDAC4HSD11B1CCR2 | |
| SCHEMBL10533434 | 0.73 | TET3 (0.49) | WDR91ALDH1A1MAPK1HDAC4HSD11B1 | |
| SCHEMBL6976227 | 0.72 | ALDH1A1 (0.35) | WDR91ALDH1A1MAPK1PTGS2HDAC4 | |
| SCHEMBL6981407 | 0.69 | CNR1 (0.37) | ALDH1A1MAPK1PTGS2HSD11B1 | |
| SCHEMBL7176061 | 0.68 | DRD2 (0.52) | ALDH1A1HDAC4HSD11B1CCR2OPRM1 | |
| SCHEMBL28755810 | 0.68 | HDAC4 (0.41) | HDAC4HSD11B1 | |
| SCHEMBL17653823 | 0.67 | WDR91 (0.61) | WDR91OPRM1 | |
| SCHEMBL11021630 | 0.67 | MAPK1 (0.47) | WDR91ALDH1A1MAPK1PTGS2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247481-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS-CHLOROMETHYL-ALKANE-CARBOXYLIC-ACID CHLORIDES | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0247481-A1 | Process for the preparation of 2,2-bis-chloromethyl-alkane-carboxylic-acid chlorides | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |