Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604944 | 0.84 | WDR91 (0.41) | TSHROPRM1HDAC4ALDH1A1 | |
| SCHEMBL4699835 | 0.82 | AKR1C1 (0.45) | LMNAAKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL28564476 | 0.80 | ELANE (0.42) | LMNATSHRCYP2C19OPRM1OPRD1 | |
| SCHEMBL28555572 | 0.79 | MAPT (0.36) | LMNATSHRCYP2C19OPRM1OPRD1 | |
| SCHEMBL6036843 | 0.78 | AKR1C1 (0.52) | LMNAAKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL9191673 | 0.77 | AKR1C1 (0.50) | AKR1C1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL12491969 | 0.75 | LMNA (0.43) | LMNATSHRKMT2AF2SMN1; SMN2 | |
| SCHEMBL373568 | 0.74 | OPRM1 (0.50) | AKR1C1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3413530 | 0.74 | ALDH1A1 (0.42) | TSHRAKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL28452149 | 0.74 | ALOX5 (0.49) | OPRM1OPRD1OPRK1OPRL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247481-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS-CHLOROMETHYL-ALKANE-CARBOXYLIC-ACID CHLORIDES | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0247481-A1 | Process for the preparation of 2,2-bis-chloromethyl-alkane-carboxylic-acid chlorides | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |