Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604466 | 0.85 | CNR1 (0.35) | ALDH1A1CNR1SMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL10575710 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GSK3AGSK3BCNR1SMN1; SMN2 | |
| SCHEMBL10607870 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL10576643 | 0.70 | BACE1 (0.39) | ALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL10604918 | 0.69 | OPRM1 (0.35) | ALDH1A1CNR1OPRM1OPRL1MEN1 | |
| SCHEMBL10576467 | 0.67 | BACE1 (0.43) | GSK3AGSK3BCNR1MEN1KMT2A | |
| SCHEMBL10576456 | 0.63 | GSK3A (0.54) | ALDH1A1GSK3AGSK3BCNR1MEN1 | |
| SCHEMBL6537130 | 0.63 | ALDH1A1 (0.42) | ALDH1A1CNR1SMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL10570645 | 0.61 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10575245 | 0.60 | ATM (0.40) | ALDH1A1CNR1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119516-B1 | 3-AMINO-TETRAHYDRO-1,3-THIAZINE-2,4-DIONES, THEIR USE AND AGENTS CONTAINING THESE COMPOUNDS FOR THE TREATMENT OF THE SKIN | Wella Aktiengesellschaft (DE) | 1989-09-20 | — | — | EP | disclosed |
| US-4654339-A | PROTECT THE SKIN AGAINST THE SUN, COLD AND AGING | WELLA AKTIENGESELLSCHAFT (DE) | 1987-03-31 | — | — | US | disclosed |
| WO-1984003699-A1 | 3-AMINO-TETRAHYDRO-1,3-THIAZINE-2,4-DIONE, UTILISATION THEREOF AND SKIN TREATMENT PRODUCT CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 1984-09-27 | — | — | WO | disclosed |
| EP-0119516-A1 | 3-Amino-tetrahydro-1,3-thiazine-2,4-diones, their use and agents containing these compounds for the treatment of the skin | Wella Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |