Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973774 | 0.84 | TAS1R3 (0.39) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10328000 | 0.81 | FOLH1 (0.42) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13628932 | 0.81 | KDM4E (0.32) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL30439625 | 0.81 | KMT2A (0.39) | ALDH1A1KDM4EMAPTCASP1THRB | |
| SCHEMBL10600585 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17995308 | 0.78 | ALDH1A1 (0.36) | ALDH1A1GAAKDM4EMAPTGLA | |
| SCHEMBL12509746 | 0.78 | SIRT1 (0.38) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21306392 | 0.77 | CA12 (0.37) | ALDH1A1GAAHPGDL3MBTL1 | |
| SCHEMBL8614577 | 0.77 | CTSS (0.51) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL13927678 | 0.77 | CTSS (0.51) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131361-B1 | COMPLEX OF BIOLOGICALLY ACTIVE PROTEIN WITH REACTIVE HIGH POLYMER HAVING BONDED THERETO BIFUNCTIONAL CHELATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4556689-A | POLYSUCCINIMIDE WITH BONDED AMINE RESIDUE OR DISULFIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-12-03 | — | — | US | disclosed |