Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492142 | 0.90 | TAS1R3 (0.39) | TAS1R3TAS1R1CA1CA2KMT2A | |
| SCHEMBL30804479 | 0.89 | TAS1R3 (0.40) | TAS1R3TAS1R1CA1CA2KMT2A | |
| SCHEMBL10359009 | 0.88 | TGFBR1 (0.36) | TAS1R3TAS1R1CA1CA2ACE | |
| SCHEMBL8618495 | 0.87 | CTSK (0.38) | TAS1R3TAS1R1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL18044129 | 0.85 | PDF (0.37) | TAS1R3TAS1R1CA1CA2ACE | |
| SCHEMBL10349090 | 0.85 | TAS1R3 (0.40) | TAS1R3TAS1R1HPGDHDAC2CTSL | |
| SCHEMBL10328000 | 0.85 | FOLH1 (0.42) | SIRT6SIRT1ALDH1A1CA1CA2 | |
| SCHEMBL8617019 | 0.84 | CTSK (0.52) | CTSLCTSSCTSK | |
| SCHEMBL10608175 | 0.84 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27541350 | 0.83 | DAGLA (0.36) | TAS1R3TAS1R1CA1CA2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143881-A | Preparation method of bumenopeptide | 深圳市健元医药科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116143881-A | Preparation method of bumenopeptide | 深圳市健元医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |