Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 6/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 6/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620690 | 0.86 | MEN1 (0.54) | ALDH1A1LMNAHTT | |
| SCHEMBL10623372 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTGSK3ARPS6KA3 | |
| SCHEMBL10708875 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTPNP | |
| SCHEMBL9298395 | 0.80 | LMNA (0.64) | LMNAABCB1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL8987656 | 0.80 | LMNA (0.64) | LMNAABCB1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL10708190 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNAABCB1HTTGSK3A | |
| SCHEMBL10623398 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAHTT | |
| SCHEMBL11644877 | 0.77 | ABCB1 (0.77) | LMNAABCB1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL441535 | 0.77 | ABCB1 (0.77) | LMNAABCB1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL5746383 | 0.76 | MEN1 (0.54) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |