Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704722 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HTTHSPA2LMNA | |
| SCHEMBL10620674 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HTTPNPLMNA | |
| SCHEMBL6273371 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBKMT2AGAA | |
| SCHEMBL6273372 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBKMT2AGAA | |
| SCHEMBL10708190 | 0.73 | ALDH1A1 (0.49) | ALDH1A1HTTPNPPOLBMEN1 | |
| SCHEMBL7830323 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HTTPOLBKMT2AGAA | |
| SCHEMBL10620684 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HTTHSPA2PNPP2RY6 | |
| SCHEMBL441997 | 0.71 | LMNA (0.66) | ALDH1A1HTTP2RY6P2RY14NT5E | |
| SCHEMBL13678671 | 0.71 | LMNA (0.66) | ALDH1A1HTTP2RY6P2RY14NT5E | |
| Hydrochloric Acid SCHEMBL11852550 | 0.70 | LMNA (0.65) | ALDH1A1HTTP2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |