Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706978 | 0.87 | MEN1 (0.56) | ALDH1A1HTTLMNAMEN1USP2 | |
| SCHEMBL10620674 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAABCB1GSK3A | |
| SCHEMBL6273371 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAPOLBKMT2A | |
| SCHEMBL6273372 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAPOLBKMT2A | |
| SCHEMBL7830323 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL10620684 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAABCB1MEN1 | |
| SCHEMBL10708875 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HTTLMNAMEN1USP2 | |
| SCHEMBL11805271 | 0.73 | LMNA (0.64) | ALDH1A1HTTLMNAABCB1GSK3A | |
| SCHEMBL14570583 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTTLMNAMEN1USP2 | |
| SCHEMBL10244723 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTTLMNAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |