Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119176 | 0.81 | LMNA (1.00) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL10801827 | 0.80 | ENPP2 (0.47) | LMNAMAPT | |
| Sulfamate SCHEMBL28644709 | 0.79 | LMNA (0.86) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9497839 | 0.78 | LMNA (0.70) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL28229310 | 0.78 | LMNA (0.54) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL10837857 | 0.77 | CA12 (0.58) | ALDH1A1HTTTSHR | |
| SCHEMBL10628554 | 0.76 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL5933830 | 0.76 | LMNA (0.69) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL3729302 | 0.75 | MAPT (0.67) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL11771545 | 0.74 | RAB9A (0.68) | LMNAALDH1A1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683930-B | Novel isoxazole compound or salt thereof | 日本欧爱特农业科技株式会社 | 2023-06-27 | — | — | CN | disclosed |
| US-11116218-B2 | Isoxazole compound or a salt thereof | OAT AGRIO CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200288717-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | OAT & IIL INDIA LABORATORIES PRIVATE LIMITED (IN) | 2020-09-17 | — | — | US | disclosed |
| EP-0181525-B1 | ANTHELMINTIC PASTE COMPOSITIONS CONTAINING RESINATES OF D,L-6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO(2,1-B)THIAZOLE | PITMAN-MOORE INC. (US) | 1992-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116218-B2 | Isoxazole compound or a salt thereof | HCN1, HAX1, HCN4 | LMNA 1947/4885ALDH1A1 566/4885SMN1; SMN2 3621/4885 |
| US-20200288717-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | HAX1, HCN1, HCN4 | LMNA 2444/4885ALDH1A1 646/4885SMN1; SMN2 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.