Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646846 | 0.82 | ALDH1A1 (0.47) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10642534 | 0.78 | GABRP (0.58) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10900569 | 0.78 | FBP1 (0.44) | FBP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL7381589 | 0.77 | LMNA (0.49) | MAPTALDH1A1GAASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10641678 | 0.77 | GABRP (0.57) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3245558 | 0.77 | CLEC4M (0.52) | FBP1MAPTNPC1MAPK1L3MBTL1 | |
| Nitric Acid SCHEMBL10644808 | 0.76 | LMNA (0.48) | MAPTALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL5897373 | 0.75 | CLEC4M (0.57) | FBP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL5897372 | 0.74 | FBP1 (0.57) | FBP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL11329048 | 0.73 | ALDH1A1 (0.49) | MAPTNPC1MAPK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |