Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.47 |
| ▸ | GABRP | O00591 | 5/20 | 0.47 |
| ▸ | GABRD | O14764 | 5/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642534 | 0.83 | GABRP (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7381589 | 0.82 | LMNA (0.49) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL10641678 | 0.81 | GABRP (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2RAB9A | |
| Nitric Acid SCHEMBL10644808 | 0.80 | LMNA (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL7383425 | 0.80 | GABRA1 (0.59) | ALDH1A1KDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL10646728 | 0.79 | ALOX5 (0.49) | ALDH1A1KDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7380334 | 0.78 | GABRA1 (0.75) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10646846 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7378994 | 0.77 | GABRA1 (0.63) | ALDH1A1KDM4EMAPTGABRA1GABRG2 | |
| SCHEMBL10705570 | 0.76 | GABRA1 (0.81) | ALDH1A1MAPTGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |