Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226562 | 0.84 | ALDH1A1 (0.54) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| Ethylene Glycol SCHEMBL29002151 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL3500543 | 0.73 | ALDH1A1 (0.43) | ALDH1A1PKMKMT2A | |
| SCHEMBL3505155 | 0.71 | ALDH1A1 (0.58) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL1333228 | 0.71 | ALDH1A1 (0.56) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL631270 | 0.71 | ALDH1A1 (0.56) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| Ethylene Glycol SCHEMBL5092855 | 0.69 | ALDH1A1 (0.51) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL21820033 | 0.69 | LMNA (0.41) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL8538536 | 0.69 | ALDH1A1 (0.40) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| Ethylene Glycol SCHEMBL4564907 | 0.69 | ALDH1A1 (0.51) | ALDH1A1PKMHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054639-A1 | In-situ stable injectable collagen-based hydrogels for cell and growth factor delivery | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-02-24 | — | — | US | disclosed |
| US-20120208291-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | UNIVERISTY OF UTAH RESEARCH FOUNDATION (US) | 2012-08-16 | — | — | US | disclosed |
| EP-2424971-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | University of Utah Research Foundation (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010127247-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208291-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | MPI, MKI67, GDI2 | ALDH1A1 4626/4885PKM 70/4885HDAC3 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.