Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649978 | 0.87 | MAPK1 (0.46) | ALDH1A1MAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL10654440 | 0.85 | MAPK1 (0.45) | ALDH1A1MAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL10570435 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1TSHRNPSR1 | |
| SCHEMBL9620470 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1POLBPKM | |
| SCHEMBL9811280 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPK1TDP1L3MBTL1POLB | |
| SCHEMBL10653026 | 0.76 | TDP1 (0.45) | ALDH1A1TDP1L3MBTL1TSHRMAPT | |
| SCHEMBL10652013 | 0.75 | VCAM1 (0.47) | ALDH1A1TDP1L3MBTL1TSHRMAPT | |
| SCHEMBL4815935 | 0.74 | TDP1 (0.54) | ALDH1A1MAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL6563367 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1TSHRNPSR1 | |
| SCHEMBL6562355 | 0.73 | NPSR1 (0.51) | ALDH1A1TDP1TSHRNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197386-A1 | 2-(Substituted sulfamyl) derivatives of 6-nitrobenzoic acid, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-10-15 | — | — | EP | disclosed |