Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055167 | 0.83 | LMNA (0.70) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL11793308 | 0.83 | KDR (0.68) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL10658648 | 0.83 | NPC1 (0.67) | MAPTLMNARAB9AGRM4MEN1 | |
| SCHEMBL3973967 | 0.82 | KDR (0.66) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL3218645 | 0.82 | CXCR2 (0.62) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL3977997 | 0.81 | KDR (0.64) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL3407832 | 0.79 | KDR (0.65) | KDRMEN1KMT2ACA1CA2 | |
| SCHEMBL28389908 | 0.79 | KDR (0.61) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL10184841 | 0.78 | KDR (0.59) | KDRPDK1MAPTLMNAGAA | |
| SCHEMBL4249329 | 0.78 | RAB9A (0.71) | KDRPDK1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728658-A | ANTIULCER | JOHN WYETH & BROTHER LIMITED (GB) | 1988-03-01 | — | — | US | claimed |
| US-4728658-A | ANTIULCER | JOHN WYETH & BROTHER LIMITED (GB) | 1988-03-01 | — | — | US | disclosed |