Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Trichlorethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichlorethanol SCHEMBL28194941 | 0.95 | — | — | |
| Trichlorethanol SCHEMBL1027 | 0.95 | — | — | |
| Trichlorethanol SCHEMBL28245853 | 0.95 | LMNA (0.36) | — | |
| Trichlorethanol SCHEMBL2024850 | 0.90 | — | — | |
| Trichlorethanol SCHEMBL9192356 | 0.90 | MEN1 (0.33) | — | |
| Trichlorethanol SCHEMBL1756486 | 0.90 | — | — | |
| Trichlorethanol SCHEMBL2902547 | 0.90 | — | — | |
| Trichlorethanol SCHEMBL7734188 | 0.86 | — | — | |
| Trichlorethanol SCHEMBL7654054 | 0.86 | — | — | |
| Trichlorethanol SCHEMBL5185962 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648180-B2 | Compound Smilaxchinoside F | Guilin Sanjin Pharmaceuticals Co., Ltd. (CN) | 2014-02-11 | — | — | US | claimed |
| US-20130090461-A1 | NEW COMPOUND SMILAXCHINOSIDE F | GUILIN SANJIN PHARMACEUTICAL CO., LTD. (CN) | 2013-04-11 | — | — | US | claimed |
| CN-116789662-A | Method for separating and purifying alkaloid compounds in phellodendron amurense by high-speed countercurrent chromatography | 山东省分析测试中心 | 2023-09-22 | — | — | CN | disclosed |
| US-20230074255-A1 | STABILIZED ALPHA-GALACTOSIDASE AND USES THEREOF | PROTALIX LTD. (IL) | 2023-03-09 | — | — | US | disclosed |
| US-10870842-B2 | Stabilized alpha-galactosidase and uses thereof | PROTALIX LTD. (IL) | 2020-12-22 | — | — | US | disclosed |
| EP-3018125-B1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | SHIN NIPPON BIOMEDICAL LABORATORIES LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| EP-3616705-A2 | COMPOSITION FOR IMPROVING PREVENTION AND TREATMENT OF FATTY LIVER CONTAININGAMOMUM VILOSUM | Corporation Ilwonbio (KR) | 2020-03-04 | — | — | EP | disclosed |
| US-20190321381-A1 | COMPOSITION COMPRISING SEA CUCUMBER EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING AND TREATING BRUCH'S MEMBRANE DYSFUNCTION-RELATED DISEASE | ALTREGEN CO., LTD. (KR) | 2019-10-24 | — | — | US | disclosed |
| EP-3556373-A1 | COMPOSITION COMPRISING SEA CUCUMBER EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING AND TREATING BRUCH'S MEMBRANE DYSFUNCTION-RELATED DISEASE | Altregen Co., Ltd. (KR) | 2019-10-23 | — | — | EP | disclosed |
| US-20190256832-A1 | STABILIZED ALPHA-GALACTOSIDASE AND USES THEREOF | PROTALIX LTD. (IL) | 2019-08-22 | — | — | US | disclosed |
| US-10280414-B2 | Stabilized α-galactosidase and uses thereof | PROTALIX LTD. (IL) | 2019-05-07 | — | — | US | disclosed |
| EP-0552489-B1 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-04 | — | — | EP | disclosed |
| WO-1997046671-A1 | ENHANCED EFFICACY OF LIPOSOMAL ANTISENSE DELIVERY | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-12-11 | — | — | WO | disclosed |
| EP-0711782-A1 | A method of preparing ganglioside | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0657471-A1 | Anti ganglioside monoclonal antibodies and their use in the specific active immunotherapy of malignant tumours | Centro de Inmunologia Molecular (CU) | 1995-06-14 | — | — | EP | disclosed |
| EP-0552489-A2 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| WO-1990003184-A1 | MATRIX WITH IMMUNOMODULATING ACTIVITY | MOREIN BROR (SE) | 1990-04-05 | — | — | WO | disclosed |
| EP-0275270-A1 | METHOD FOR THE RADIOIODATION OF GANGLIOSIDES BY ENZYMATIC PROCESS. | CENTRE NAT RECH SCIENT (FR) | 1988-07-27 | — | — | EP | disclosed |
| WO-1988000175-A1 | METHOD FOR THE RADIOIODATION OF GANGLIOSIDES BY ENZYMATIC PROCESS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-01-14 | — | — | WO | disclosed |
| US-3981927-A | INHALATION ANESTHETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |