Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG2 | P78540 | 6/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 5/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | ODC1 | P11926 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854796 | 0.97 | ARG2 (0.52) | ARG2GPR84FFAR1FFAR4ARG1 | |
| SCHEMBL8678281 | 0.95 | ARG2 (0.50) | ARG2GPR84FFAR1FFAR4ARG1 | |
| SCHEMBL442848 | 0.83 | — | — | |
| SCHEMBL9403239 | 0.82 | NFKB1 (0.52) | ARG2GPR84FFAR1FFAR4CAMK2A | |
| SCHEMBL6632838 | 0.79 | ODC1 (0.56) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL288685 | 0.77 | FDPS (0.46) | ARG2GPR84FFAR1FFAR4ARG1 | |
| SCHEMBL2587404 | 0.77 | ODC1 (0.48) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL497881 | 0.77 | LMNA (0.48) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| SCHEMBL29290 | 0.75 | LMNA (0.52) | GPR84FFAR1FFAR4LMNABLM | |
| SCHEMBL3624118 | 0.75 | ARG1 (0.35) | ARG2ARG1ODC1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746649-A | Diamino acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0161588-A2 | Diamino acid derivatives | MERCK PATENT GmbH (DE) | 1985-11-21 | — | — | EP | disclosed |