Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CRHBP | P24387 | 2/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.63 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615498 | 0.88 | CRHBP (0.67) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 | |
| SCHEMBL28711028 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 | |
| SCHEMBL5956066 | 0.82 | LMNA (0.57) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 | |
| SCHEMBL10658746 | 0.80 | VCAM1 (0.44) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL11749307 | 0.79 | SLC25A1 (0.68) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 | |
| SCHEMBL7588981 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTCRHBPCRHR2GAA | |
| SCHEMBL10661530 | 0.77 | CRHBP (0.71) | ALDH1A1MAPTCRHBPCRHR2LMNA | |
| SCHEMBL28701969 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 | |
| SCHEMBL28821820 | 0.77 | HPGD (0.70) | ALDH1A1MAPTCRHBPCRHR2LMNA | |
| SCHEMBL29507647 | 0.77 | MAPT (0.69) | ALDH1A1MAPTCRHBPCRHR2SLC25A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292911-A2 | Process for the preparation of pure nitro-aminobenzene-compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |