Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 18/20 | 0.52 |
| ▸ | PYGM | P11217 | 18/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865516 | 0.89 | PYGL (0.48) | PYGLPYGMALDH1A1 | |
| SCHEMBL10540860 | 0.88 | PYGM (0.39) | PYGLPYGMALDH1A1 | |
| SCHEMBL9867642 | 0.87 | PYGL (0.46) | PYGLPYGMALDH1A1 | |
| SCHEMBL30157261 | 0.86 | PYGM (0.62) | PYGLPYGM | |
| SCHEMBL4072118 | 0.86 | PYGM (0.62) | PYGLPYGM | |
| SCHEMBL9557790 | 0.84 | KDM4E (0.38) | PYGLPYGMALDH1A1 | |
| SCHEMBL9865957 | 0.83 | PYGL (0.44) | PYGLPYGMALDH1A1 | |
| SCHEMBL9865950 | 0.83 | PYGM (0.52) | PYGLPYGM | |
| SCHEMBL8804777 | 0.82 | PYGM (0.37) | PYGLPYGMALDH1A1 | |
| SCHEMBL10649530 | 0.82 | PYGL (0.39) | PYGLPYGMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721719-A | Dihydropyridinelactols and their use as medicaments which influence blood sugar | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |