SCHEMBL9865950

SCHEMBL9865950

CCOC(C)OC(=O)C1=C(C)N(CC)C2=C(C(=O)OC2)C1c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PYGM P11217 19/20 0.52
PYGL P06737 18/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4072118 0.91 PYGM (0.62) PYGMPYGL
SCHEMBL30157261 0.91 PYGM (0.62) PYGMPYGL
SCHEMBL9865516 0.88 PYGL (0.48) PYGMPYGL
SCHEMBL9867642 0.84 PYGL (0.46) PYGMPYGL
SCHEMBL9865957 0.83 PYGL (0.44) PYGMPYGL
SCHEMBL10659301 0.83 PYGL (0.52) PYGMPYGL
SCHEMBL9864934 0.81 PYGM (0.49) PYGMPYGL
SCHEMBL9829022 0.79 PYGL (0.48) PYGMPYGL
SCHEMBL10649530 0.78 PYGL (0.39) PYGMPYGL
SCHEMBL9865794 0.78 PYGM (0.46) PYGMPYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026714-A Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabetics BAYER AKTIENGESELLSCHAFT (DE) 1991-06-25 US claimed