Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NMBR | P28336 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106421 | 0.83 | ADRB2 (0.44) | L3MBTL1 | |
| SCHEMBL4402023 | 0.83 | ADRB2 (0.44) | L3MBTL1 | |
| SCHEMBL4758614 | 0.79 | TSHR (0.43) | L3MBTL1 | |
| SCHEMBL3094213 | 0.78 | TDP1 (0.51) | PPARGMME | |
| SCHEMBL5089560 | 0.77 | CTSK (0.45) | PPARGCTSKL3MBTL1 | |
| SCHEMBL5086244 | 0.77 | CTSK (0.45) | PPARGCTSKL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27464326 | 0.76 | L3MBTL1 (0.47) | PPARGL3MBTL1MME | |
| SCHEMBL3090625 | 0.75 | TGFBR1 (0.47) | MMETGFBR1 | |
| SCHEMBL10347904 | 0.75 | ALOX5 (0.49) | KDM4EPPARGALOX5CHRM5CHRM1 | |
| SCHEMBL29012364 | 0.74 | CTSK (0.53) | CTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |