Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.56 |
| ▸ | ATP4B | P51164 | 2/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466220 | 0.81 | ALDH1A1 (0.67) | ATP4AATP4BPTGDR2KDM4EALDH1A1 | |
| SCHEMBL10661906 | 0.80 | ATP4A (0.67) | ATP4AATP4BPTGDR2ALDH1A1MAPT | |
| SCHEMBL10662994 | 0.79 | ATP4A (0.73) | ATP4AATP4BPTGDR2ALDH1A1MAPT | |
| SCHEMBL8005690 | 0.76 | PTGDR2 (0.68) | ATP4AATP4BPTGDR2KDM4ECYP1A2 | |
| SCHEMBL10661908 | 0.72 | ATP4A (1.00) | ATP4AATP4B | |
| SCHEMBL8108204 | 0.70 | MTNR1A (0.42) | ALDH1A1POLBMAPT | |
| SCHEMBL727669 | 0.70 | ATP4A (0.63) | ATP4AATP4BPTGDR2 | |
| SCHEMBL718120 | 0.70 | PTGDR2 (0.54) | ATP4AATP4BPTGDR2KDM4EALDH1A1 | |
| SCHEMBL729142 | 0.69 | ATP4A (0.61) | ATP4AATP4BPTGDR2KDM4EALDH1A1 | |
| SCHEMBL10659751 | 0.68 | ATP4A (0.66) | ATP4AATP4BPTGDR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |