Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665142 | 0.84 | GPBAR1 (0.38) | GPBAR1MAPTKMT2A | |
| SCHEMBL10732274 | 0.78 | GPBAR1 (0.42) | GPBAR1MAPTMEN1KMT2APTGS1 | |
| SCHEMBL11016217 | 0.74 | GPBAR1 (0.35) | GPBAR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11258956 | 0.72 | PTGDR2 (0.42) | GPBAR1MAPT | |
| SCHEMBL10655898 | 0.67 | KMT2A (0.38) | GPBAR1MAPTMEN1KMT2APTGS1 | |
| SCHEMBL10663342 | 0.67 | PKM (0.43) | GPBAR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10663114 | 0.66 | PPARA (0.44) | GPBAR1MAPTMEN1KMT2APTGS1 | |
| SCHEMBL11560907 | 0.66 | PTGS1 (0.43) | GPBAR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4035353 | 0.66 | FFAR4 (0.44) | GPBAR1PTGS1ALDH1A1 | |
| SCHEMBL10657879 | 0.65 | MAPT (0.39) | GPBAR1MAPTMEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |