Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684504 | 0.88 | CDC7 (0.40) | NAPRTKDM4ETSHRMAPTL3MBTL1 | |
| SCHEMBL10677472 | 0.85 | NPC1 (0.38) | NAPRTKDM4EHPGDHSD17B10TSHR | |
| SCHEMBL10676194 | 0.85 | ALDH1A1 (0.52) | GAAKDM4EHPGDTSHRMAPT | |
| SCHEMBL10678506 | 0.84 | CYP1A2 (0.39) | NAPRTKDM4ETSHRMAPTL3MBTL1 | |
| SCHEMBL10679720 | 0.81 | PDE3B (0.45) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10681150 | 0.78 | UCHL1 (0.50) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10672837 | 0.78 | CCND3 (0.38) | KDM4ETSHRMAPTL3MBTL1CYP1A2 | |
| SCHEMBL10681743 | 0.77 | PDE3B (0.53) | NAPRTGAAKDM4EHPGDHSD17B10 | |
| SCHEMBL10684520 | 0.77 | UCHL1 (0.46) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10677653 | 0.75 | UCHL1 (0.53) | GAAKDM4EHPGDMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |