Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675813 | 0.85 | NAPRT (0.43) | KDM4ESMN1; SMN2L3MBTL1CYP1A2MAPT | |
| SCHEMBL10678506 | 0.85 | CYP1A2 (0.39) | NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL10684504 | 0.84 | CDC7 (0.40) | KDM4ESMN1; SMN2L3MBTL1CYP1A2MAPT | |
| SCHEMBL10676194 | 0.84 | ALDH1A1 (0.52) | NPC1RAB9AKDM4EL3MBTL1MAPT | |
| SCHEMBL10679720 | 0.82 | PDE3B (0.45) | KDM4ESMN1; SMN2L3MBTL1CYP1A2MAPT | |
| SCHEMBL10677717 | 0.80 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10672837 | 0.79 | CCND3 (0.38) | NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL10681806 | 0.77 | PDE3B (0.55) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10678457 | 0.77 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL10681162 | 0.75 | ALDH1A1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |