Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663049 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1GPR35CA12 | |
| SCHEMBL28357039 | 0.83 | TDP1 (0.57) | ALDH1A1TSHRTDP1GPR35CA12 | |
| SCHEMBL11189712 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL14907881 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL11693636 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL29126640 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL843884 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL10679746 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL3962914 | 0.81 | CYP1A2 (0.51) | ALDH1A1TSHRTDP1GPR35NPC1 | |
| SCHEMBL9780752 | 0.81 | NPC1 (0.48) | ALDH1A1TSHRTDP1GPR35NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101935281-A | Method for preparing m-nitrochlorobenzene, o-nitrochlorobenzene and p-nitrochlorobenzene by using nitrochlorobenzene meta-position oil | SHAOYANG CITY SHENQIANG CHEMICAL CO LTD | 2011-01-05 | — | — | CN | claimed |
| CN-115594592-B | Preparation method and application of 2-chloro-3-nitrobenzoic acid | 江西天宇化工有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-115594592-A | Preparation method and application of 2-chloro-3-nitrobenzoic acid | 江西天宇化工有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-104511476-B | A method of accelerating organic contaminants in soil oxidative degradation | 江苏迈克环境工程有限公司 | 2019-05-31 | — | — | CN | disclosed |
| US-10005731-B2 | Modulators of the retinoid-related orphan receptor gamma (ROR-gamma) for use in the treatment of autoimmune and inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2018-06-26 | — | — | US | disclosed |
| US-10005731-B2 | Modulators of the retinoid-related orphan receptor gamma (ROR-gamma) for use in the treatment of autoimmune and inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2018-06-26 | — | — | US | disclosed |
| US-10005731-B2 | Modulators of the retinoid-related orphan receptor gamma (ROR-gamma) for use in the treatment of autoimmune and inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2018-06-26 | — | — | US | disclosed |
| WO-2017160552-A1 | DOPAMINE D3 RECEPTOR SELECTIVE ANTAGONISTS/PARTIAL AGONISTS; METHOD OF MAKING; AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-09-21 | — | — | WO | disclosed |
| EP-3219711-A1 | MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR-GAMMA) FOR USE IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES | Glaxo Group Limited (GB) | 2017-09-20 | — | — | EP | disclosed |
| EP-3219711-A1 | MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR-GAMMA) FOR USE IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES | Glaxo Group Limited (GB) | 2017-09-20 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0282944-B1 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL IND LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| CN-1023011-C | Herbicide composition containing pyrazole derivative | NISSAN CHEMICAL IND LTD (JP) | 1993-12-08 | — | — | CN | disclosed |
| US-5175299-A | Benzoic acid derivatives useful as intermediates for the preparation of herbicidal 4-benzoylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5143915-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |
| US-4948887-A | FOR UPLAND FIELDS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4885022-A | Herbicidal pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| CN-88101455-A | Pyrazole derivatives and herbicides containing the same | — | 1988-09-28 | — | — | CN | disclosed |
| EP-0282944-A2 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005731-B2 | Modulators of the retinoid-related orphan receptor gamma (ROR-gamma) for use in the treatment of autoimmune and inflammatory diseases | RORB, RORC, RORA | ALDH1A1 1045/4885TSHR 95/4885TDP1 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.