Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178730 | 0.84 | PTGS2 (0.40) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL8031056 | 0.74 | PTGS2 (0.53) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL6907494 | 0.74 | PTGS2 (0.41) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL1067728 | 0.72 | MAOA (0.50) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL29049090 | 0.72 | CD69 (0.53) | MAOAMAOBMTNR1AMTNR1B | |
| SCHEMBL4442002 | 0.70 | MAOA (0.45) | MAOAMAOBPTGS2GPR84MTNR1A | |
| SCHEMBL30586108 | 0.70 | GPR84 (0.45) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL16434673 | 0.69 | MAOA (0.43) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL7423243 | 0.69 | PTGS2 (0.41) | MAOAMAOBPTGS2CYP11B2CYP11B1 | |
| SCHEMBL19979197 | 0.69 | PTGS2 (0.41) | MAOAMAOBPTGS2CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868797-B2 | Bridged metallocene complex for olefin polymerization | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2018-01-16 | — | — | US | disclosed |
| US-9828447-B2 | Process for the preparation of 2,2′-bis-indenyl biphenyl ligands and their metallocene complexes | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2017-11-28 | — | — | US | disclosed |
| US-20160194414-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIS-INDENYL BIPHENYL LIGANDS AND THEIR METALLOCENE COMPLEXES | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2016-07-07 | — | — | US | disclosed |
| US-20160168280-A1 | BRIDGED METALLOCENE COMPLEX FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194414-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIS-INDENYL BIPHENYL LIGANDS AND THEIR METALLOCENE COMPLEXES | CYP1B1, PCBP1, IGF2BP3 | MAOA 1265/4885MAOB 461/4885PTGS2 2094/4885 |
| US-20160168280-A1 | BRIDGED METALLOCENE COMPLEX FOR OLEFIN POLYMERIZATION | ZYX, PYM1, OPRM1 | MAOA 1975/4885MAOB 1774/4885PTGS2 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.