Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678457 | 0.90 | LMNA (0.40) | ALDH1A1LMNAMAPTL3MBTL1GAA | |
| SCHEMBL10682046 | 0.88 | MAPT (0.48) | ALDH1A1LMNAMAPTGAARAB9A | |
| SCHEMBL10681969 | 0.87 | MAPT (0.47) | ALDH1A1LMNAAKR1C3MAPTL3MBTL1 | |
| SCHEMBL10681806 | 0.87 | PDE3B (0.55) | ALDH1A1LMNAMAPTHPGDUCHL1 | |
| SCHEMBL10681150 | 0.87 | UCHL1 (0.50) | ALDH1A1LMNAAKR1C3MAPTL3MBTL1 | |
| SCHEMBL10676837 | 0.86 | CDC7 (0.42) | ALDH1A1LMNAAKR1C3MAPTL3MBTL1 | |
| SCHEMBL10681674 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTL3MBTL1GAA | |
| SCHEMBL7384614 | 0.84 | PDE3B (0.47) | ALDH1A1LMNAAKR1C3MAPTL3MBTL1 | |
| SCHEMBL10682007 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTL3MBTL1GAA | |
| SCHEMBL10680630 | 0.84 | NPC1 (0.34) | ALDH1A1LMNAMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |