Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852499 | 0.83 | KMT2A (0.40) | PTGS1GSTP1GSTM2CXCR1CXCR2 | |
| SCHEMBL9748843 | 0.81 | PTGS1 (0.38) | PTGS1GSTP1GSTM2CCNB2CCNE2 | |
| SCHEMBL10688854 | 0.74 | HSD17B10 (0.43) | ALDH1A1KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL9748003 | 0.73 | PTGS1 (0.36) | PTGS1GSTP1GSTM2CXCR1CXCR2 | |
| SCHEMBL9852546 | 0.73 | PTGS1 (0.36) | PTGS1GSTP1GSTM2CXCR1CXCR2 | |
| SCHEMBL10690505 | 0.71 | NPSR1 (0.38) | ALDH1A1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL9627261 | 0.70 | KDM4E (0.43) | ALDH1A1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL15737155 | 0.69 | KMT2A (0.43) | PTGS1GSTP1GSTM2CXCR1CXCR2 | |
| SCHEMBL22589563 | 0.68 | GRM6 (0.38) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16311074 | 0.68 | ALDH1A1 (0.36) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |