Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627261 | 0.86 | KDM4E (0.43) | KMT2AALDH1A1MEN1RAB9AKDM4E | |
| SCHEMBL10685904 | 0.83 | APEX1 (0.43) | ALDH1A1KDM4EMAPK1HSD17B10TSHR | |
| SCHEMBL10685641 | 0.83 | PTGS1 (0.39) | KMT2APTGS1GSTP1GSTM2CXCR1 | |
| SCHEMBL9748003 | 0.81 | PTGS1 (0.36) | KMT2APTGS1GSTP1GSTM2CXCR1 | |
| SCHEMBL9852546 | 0.78 | PTGS1 (0.36) | KMT2APTGS1GSTP1GSTM2CXCR1 | |
| SCHEMBL10692166 | 0.78 | ALDH1A1 (0.44) | CXCR1CXCR2ALDH1A1KDM4ETSHR | |
| SCHEMBL9748006 | 0.77 | KDM4E (0.42) | ALDH1A1RAB9AKDM4EMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL16593684 | 0.75 | KDM4E (0.41) | ALDH1A1RAB9AKDM4EMAPK1HSD17B10 | |
| SCHEMBL10688854 | 0.74 | HSD17B10 (0.43) | KMT2AALDH1A1MEN1KDM4EFFAR1 | |
| SCHEMBL10688331 | 0.73 | CYP1A2 (0.43) | KMT2AALDH1A1KDM4EFFAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409055-A1 | Cephalosporin derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |